Trevi Fountain in Rome, Italy -- "the fountain at the junction of three roads." Throw a coin into the fountain, and legend has it that you will return to Rome. I wish I'd tossed a coin in while I was there!
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Florence - Sunset over Arno by Giuseppe Torre :( I miss it SO MUCH. And I must get back here someday so I can get to the top of Il Duomo, and watch the sunset on the Arno from the top of San Michaelangelo.