2014 Rashtak. Review Article: Celiac Disease, New Approaches to Therapy. Aactive celiac disease has epithelial barrier defect that leads to incr permeability and possibly passage of immunodominant gluten peptides and likely other immunostimulatory luminal antigens, esp bacterial components. Many invest are discussed for treatment of celiac disease. Peptides, Celiac Disease, Disease, Celiac, Gluten Withdrawal, Components, Treatment, Approach, Gluten